Chinese scientists published a paper on Nature on the “Digestive symptoms of CCP-virus and expression of ACE2 in digestive tract organs”.
It has been established that SARS-CoV-2 (CCP-virus) invades host cells by binding to the transmembrane receptor Angiotensin-converting enzyme 2 (ACE2).
In addition to the common symptoms like fever, fatigue, cough, myalgia, and dyspnea, some patients may suffer from digestive system symptoms, such as pharyngalgia, diarrhea, nausea, vomiting, and abdominal pain, suggesting that the digestive tract organs also may be targeted by the virus.
Digestive symptoms of 48 patients in a Guangzhou hospital were assessed by some Chinese researchers. “The results showed that nearly a quarter of COVID-19 patients had gastrointestinal symptoms, that ACE2 expression was higher in the digestive tract than the lung, and the ratio of ACE2-positive cells in tumor tissues was higher than that in paracancerous normal tissue” according to their study.